Cu2+ complexes of some AGE inhibitors.

Show simple item record

dc.contributor.author Ortega Castro, Joaquín
dc.contributor.author Muñoz Izquierdo, Francisco
dc.contributor.author Donoso Pardo, Josefa Laurentina
dc.contributor.author Frau Munar, Juan
dc.contributor.author Adrover Estelrich, Miguel
dc.date.accessioned 2018-11-22T10:16:22Z
dc.identifier.uri http://hdl.handle.net/11201/148574
dc.description.abstract [eng] UB3LYP/6-31+G∗ calculations were used to elucidate the structures of the complexes of Cu2+ with various ligands including aminoguanidine, pyridoxamine, Amadori compound and ascorbic acid. The solvent effect was simulated by using the CPCM method. The square-planar chelate containing two ligand molecules was found to be the most stable form in all complexes. The stability of the different chelates was consistent with the facts that aminoguanidine inhibits the oxidation of ascorbic acid but not that of Amadori compounds, whereas pyridoxamine inhibits both.
dc.format application/pdf
dc.relation.isformatof Versió postprint del document publicat a: https://doi.org/10.1016/J.CPLETT.2009.05.074
dc.relation.ispartof Chemical Physics Letters, 2009, vol. 475, p. 277-284
dc.subject.classification 54 - Química
dc.subject.other 54 - Chemistry. Crystallography. Mineralogy
dc.title Cu2+ complexes of some AGE inhibitors.
dc.type info:eu-repo/semantics/article
dc.type info:eu-repo/semantics/acceptedVersion
dc.date.updated 2018-11-22T10:16:22Z
dc.date.embargoEndDate info:eu-repo/date/embargoEnd/2075-01-01
dc.embargo 2075-01-01
dc.subject.keywords Chemical Kinetics
dc.subject.keywords Pyridoxamine (PM)
dc.subject.keywords DFT
dc.subject.keywords AGE
dc.subject.keywords Cu (II) complexes
dc.rights.accessRights info:eu-repo/semantics/embargoedAccess
dc.identifier.doi https://doi.org/10.1016/J.CPLETT.2009.05.074


Files in this item

This item appears in the following Collection(s)

Show simple item record