Cu2+ complexes of some AGE inhibitors.

Show simple item record Ortega Castro, Joaquín Muñoz Izquierdo, Francisco Donoso Pardo, Josefa Laurentina Frau Munar, Juan Adrover Estelrich, Miguel 2018-11-22T10:16:22Z
dc.description.abstract [eng] UB3LYP/6-31+G∗ calculations were used to elucidate the structures of the complexes of Cu2+ with various ligands including aminoguanidine, pyridoxamine, Amadori compound and ascorbic acid. The solvent effect was simulated by using the CPCM method. The square-planar chelate containing two ligand molecules was found to be the most stable form in all complexes. The stability of the different chelates was consistent with the facts that aminoguanidine inhibits the oxidation of ascorbic acid but not that of Amadori compounds, whereas pyridoxamine inhibits both.
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dc.relation.isformatof Versió postprint del document publicat a:
dc.relation.ispartof Chemical Physics Letters, 2009, vol. 475, p. 277-284
dc.subject.classification 54 - Química
dc.subject.other 54 - Chemistry. Crystallography. Mineralogy
dc.title Cu2+ complexes of some AGE inhibitors.
dc.type info:eu-repo/semantics/article
dc.type info:eu-repo/semantics/acceptedVersion 2018-11-22T10:16:22Z info:eu-repo/date/embargoEnd/2075-01-01
dc.embargo 2075-01-01
dc.subject.keywords Chemical Kinetics
dc.subject.keywords Pyridoxamine (PM)
dc.subject.keywords DFT
dc.subject.keywords AGE
dc.subject.keywords Cu (II) complexes
dc.rights.accessRights info:eu-repo/semantics/embargoedAccess

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