Association between lifestyle and hypertriglyceridemic waist phenotype in the PREDIMED-Plus study

Show simple item record Fernández-García, J.C. Muñoz-Garach, A. Martínez-González, M.A. Salas-Salvado, J. Corella, D. Hernáez, A. Romaguera, D. Vioque, J. Alonso-Gómez, A.M. Wärnberg, J. Martínez, J.A. Serra-Majem, L. Estruch, R. Lapetra, J. Pintó, X. Tur, J.A. Garcia-Rios, A. García Molina, L. Gaforio, J.J. Matía-Martín, P. Daimiel, L. Martín Sánchez, V. Vidal, J. Prieto, L. Ros, E. Goñi, N. Babio, N. Ortega-Azorin, C. Castañer, O. Konieczna, J. Notario Barandiaran, L. Vaquero-Luna, J. Benavente-Marín, J.C. Zulet, M.A. Sanchez-Villegas, A. Sacanella, E. Gómez Huelgas, R. Miró-Moriano, L. Gimenez-Gracia, M. Julibert, A. 2020-03-18T09:03:09Z
dc.description.abstract [eng] Objective: The hypertriglyceridemic waist (HTGW) phenotype is charac-terized by abdominal obesity and high levels of triglycerides. In a cross-sectional assessment of PREDIMED-Plus trial participants at baseline, HTGW phenotype prevalence was evaluated, associated risk factors were analyzed, and the lifestyle of individuals with metabolic syndrome and HTGW was examined.Methods: A total of 6,874 individuals aged 55 to 75 with BMI ≥ 27 and < 40 kg/m2 were included and classified by presence (HTGW+) or absence (HTGW−) of HTGW (waist circumference: men ≥ 102 cm, women ≥ 88 cm; fasting plasma triglycerides ≥ 150 mg/dL). Analytical parameters and life-style (energy intake and expenditure) were analyzed.Results: A total of 38.2% of the sample met HTGW+ criteria. HTGW+individuals tended to be younger, have a greater degree of obesity, be sedentary, and be tobacco users. They had higher peripheral glucose, total cholesterol, and low-density lipoprotein cholesterol levels; had lower high-density lipoprotein cholesterol levels; and had increased prevalence of type 2 diabetes mellitus. Mediterranean diet (MedDiet) adherence and physical activity were greater in HTGW− patients. Age, BMI, tobacco use, total energy expenditure, hypertension, type 2 diabetes mellitus, and MedDiet adherence were associated with HTGW+.Conclusions: HTGW is a highly prevalent phenotype in this population associated with younger age, higher BMI, tobacco use, and decreased MedDiet adherence. HTGW− individuals were more physically active with greater total physical activity, and fewer had hypertension
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dc.relation.isformatof Versió preprint del document publicat a:
dc.relation.ispartof Obesity, 2020, vol. 28, num. 3, p. 537-543
dc.rights (c) The Obesity Society, 2020
dc.subject.classification 57 - Biologia
dc.subject.classification Ciències de la salut
dc.subject.other 57 - Biological sciences in general
dc.subject.other Medical sciences
dc.title Association between lifestyle and hypertriglyceridemic waist phenotype in the PREDIMED-Plus study
dc.type info:eu-repo/semantics/article
dc.type info:eu-repo/semantics/submittedVersion 2020-03-18T09:03:10Z info:eu-repo/date/embargoEnd/2026-12-31
dc.embargo 2026-12-31
dc.rights.accessRights info:eu-repo/semantics/embargoedAccess

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