Recerca bibliogràfica sobre el paper de la leptina durant la gestació i la lactància sobre la prevenció de l'obesitat en edat adulta

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dc.contributor Picó Segura, Catalina Mascaró Bennasar, Francisca Maria 2015-09-15T07:51:55Z 2015-09-15T07:51:55Z 2015-09-15
dc.description.abstract Obesity is one of the risk factors of various chronic diseases. It may result from excess accumulation of body fat. This condition may be caused by dysfunction of appetite-regulating pathways and energy balance due to leptin resistance. Leptin, a 16 kDa hormone, is the most important regulator of appetite and energy balance in the body and it is involved in the interaction between peripheral signals and brain target. . Leptin is mainly produced by the adipose tissue, but also by the stomach, the placenta and the mammary gland and it is present in maternal milk (but not in infant formula). In addition to its effects on normal concepts development, this hormone is linked to mechanisms affecting a diverse array of pregnancy-specific pathologies that include preeclampsia, gestational diabetes, and intrauterine growth restriction that affect the individual's health in adult life, such as obesity, cardiovascular disease and metabolic syndrome. Different studies of experimental models that analyze glucose, insulin and leptin under different conditions indicate that animals supplemented with physiological doses of leptin during lactation were more protected against obesity and metabolic diseases. In humans, association studies suggested that milk-borne leptin provides a link between maternal body composition and infant growth and development, and plays a critical role in regulating appetite and food intake during early infancy. Thus, moderate milk-borne maternal leptin appears to provide moderate protection to infants from an excess of weight gain, and milk leptin may be factor that could explain, at least partially, the higher propensity to develop obesity that show formula-fed infants with respect to breast-fed infants. ca
dc.language.iso cat ca
dc.subject.classification Matèries generals UIB::Biologia ca
dc.title Recerca bibliogràfica sobre el paper de la leptina durant la gestació i la lactància sobre la prevenció de l'obesitat en edat adulta ca
dc.type info:eu-repo/semantics/bachelorThesis ca
dc.subject.keywords Obesity ca
dc.subject.keywords Obesitat ca
dc.subject.keywords Leptin ca
dc.subject.keywords Leptina ca
dc.subject.keywords Leptin resistance ca
dc.subject.keywords Resistència a la leptina ca
dc.subject.keywords Energy homoeostasis ca
dc.subject.keywords Energia homeostàtica ca
dc.subject.keywords Metabolic programming ca
dc.subject.keywords Programació metabòlica ca
dc.subject.keywords Hypothalamus development ca
dc.subject.keywords Desenvolupament hipotàlem ca
dc.subject.keywords Breastfeeding ca
dc.subject.keywords Lactància materna ca
dc.subject.keywords Early life nutrition ca
dc.subject.keywords Nutrició en els primers anys ca
dc.subject.keywords Infant formula ca
dc.subject.keywords Llet maternitzada ca
dc.subject.keywords Lactation ca
dc.subject.keywords Lactància ca
dc.subject.keywords Milk leptin ca
dc.subject.keywords Leptina de la llet ca
dc.subject.keywords Leptin sensitivity ca
dc.subject.keywords Sensibilitat a la leptina ca
dc.subject.keywords Oral leptin ca
dc.subject.keywords Leptina oral ca

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