dc.contributor.author |
Rodas Ceballos, Melisa Alejandra
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dc.contributor.author |
Portugal, Lindomar A.
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dc.contributor.author |
Avivar, Jessica
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dc.contributor.author |
Estela Ripoll, José Manuel
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dc.contributor.author |
Cerdà Martín, Víctor
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dc.date.accessioned |
2018-10-29T11:56:43Z |
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dc.identifier.uri |
http://hdl.handle.net/11201/148314 |
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dc.description.abstract |
[eng] Parabensarewidelyusedindairyproducts,suchasincosmeticsandpersonalcareproducts.Thus,inthis workamulti-syringechromatographic(MSC)systemisproposedforthe first timeforthedetermination of fourparabens:methylparaben(MP),ethylparaben(EP),propylparaben(PP)andbutylparaben(BP)in cosmetics andpersonalcareproducts,asasimpler,practical,andlowcostalternativetoHPLCmethods. Separation wasachievedusinga5mm-longprecolumnofreversedphaseC18andmulti-isocratic separation, i.e.usingtwoconsecutivemobilephases,12:88acetonitrile:waterand28:72acetonitrile: water.Theuseofamulti-syringeburetallowedtheeasyimplementationofchemiluminescent(CL) detection afterseparation.ThechemiluminescentdetectionisbasedonthereductionofCe(IV)by p-hydroxybenzoicacid,productoftheacidhydrolysisofparabens,toexciterhodamine6G(Rho6G)and measure theresultinglightemission.Multivariatedesignscombinedwiththeconceptsofmultiple response treatmentsanddesirabilityfunctionshavebeenemployedtosimultaneouslyoptimizeand evaluatetheresponses.Theoptimizedmethodhasprovedtobesensitiveandprecise,obtaininglimitsof detection between20and40 mg L 1 and RSD o4.9% inallcases.Themethodwassatisfactorilyapplied to cosmeticsandpersonalcareproducts,obtainingnosignificant differencesataconfidence levelof95% comparing withtheHPLCreferencemethod. |
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dc.format |
application/pdf |
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dc.relation.isformatof |
Versió postprint del document publicat a: |
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dc.relation.ispartof |
Talanta, 2015, num. 143, p. 254-262 |
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dc.rights |
(c) Elsevier B.V., 2015 |
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dc.title |
Parabenos determination in cosmetic and personal care products Exploiting a Multi-Syringe Chromatographic (MSC) system and chemiluminescent detection |
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dc.type |
info:eu-repo/semantics/article |
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dc.type |
info:eu-repo/semantics/acceptedVersion |
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dc.date.updated |
2018-10-29T11:56:44Z |
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dc.date.embargoEndDate |
info:eu-repo/date/embargoEnd/2075-01-01 |
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dc.embargo |
2075-01-01 |
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dc.rights.accessRights |
info:eu-repo/semantics/embargoedAccess |
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