Effects of depressive symptoms on clinical outcomes, inflammatory markers and quality of life after a significant weight loss in a bariatric surgery sample

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dc.contributor.author Nicolau, J.
dc.contributor.author Simó, R.
dc.contributor.author Sanchís, P.
dc.contributor.author Ayala, L.
dc.contributor.author Fortuny, R.
dc.contributor.author Rivera, R.
dc.contributor.author Masmiquel, L.
dc.date.accessioned 2020-01-10T08:49:39Z
dc.date.available 2020-01-10T08:49:39Z
dc.identifier.uri http://hdl.handle.net/11201/150552
dc.description.abstract [eng] INTRODUCTION: Obesity is linked to a low-grade chronic systemic inflammation that improves after weight loss. Depressive disorder has been suggested to be associated with systemic inflammation up regulation. OBJECTIVE: We aimed to explore whether, after a significant weight loss, the presence of depressive symptoms was associated with differences in terms of inflammatory markers and quality of life. METHODS: Sixty patients (78.3%♀, age 46.4 ± 9.9) who underwent bariatric surgery, with a minimum follow up of 18 months, were evaluated. For the screening of depression, the Beck Depression Inventory (BDI) was administered. RESULTS: Ten subjects (16.6%) had a positive screening for depressive disorder. The percentage of patients with weight regain was greater among subjects with symptoms of depression (70% vs. 32%; p = 0.024), although no differences were seen regarding BMI prior to surgery and current BMI. Acute phase reactants were higher among subjects with symptoms of depression: platelets (319 ± 15 x 10^12/L vs. 232 ± 47 x 10 ^ 12/L; p = 0.001), erythrocyte sedimentation rate (24.7 ± 11.3 mm vs.17 ± 10 mm; p = 0.03), fibrinogen (486 ± 107 mg/dL vs. 406 ± 66 mg/dL; p = 0.003), ferritin (106 ± 180 ng/ml vs. 34 ± 44 ng/ml; p = 0.014) and ultrasensitive C-reactive protein (0.96 ± 1.84 mg/dL vs. 0.24 ± 0.26 mg/dL; p = 0.008). All domains of quality of life were significantly lower in the depressive group. CONCLUSIONS: Despite a significant weight loss, inflammatory markers are greater and quality of life lower when associated with depressive symptoms.
dc.format application/pdf
dc.relation.isformatof Reproducció del document publicat a: https://doi.org/10.20960/nh.979
dc.relation.ispartof Nutrición Hospitalaria, 2017, vol. 34, num. 1, p. 81-87
dc.rights (c) Nutrición Hospitalaria, 2017
dc.subject.classification Nutrició
dc.subject.classification 663/664 - Aliments i nutrició. Enologia. Olis. Greixos
dc.subject.other Nutrition
dc.subject.other 663/664 Beverages. Estimulants. Food industry. Preservation
dc.title Effects of depressive symptoms on clinical outcomes, inflammatory markers and quality of life after a significant weight loss in a bariatric surgery sample
dc.type info:eu-repo/semantics/article
dc.type info:eu-repo/semantics/publishedVersion
dc.date.updated 2020-01-10T08:49:40Z
dc.subject.keywords depressive symptoms
dc.subject.keywords inflammatory markers
dc.subject.keywords cirugía bariátrica
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.identifier.doi https://doi.org/10.20960/nh.979

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