A novel Ca2+ signaling pathway coordinates environmental phosphorus sensing and nitrogen metabolism in marine diatoms.

Show simple item record

dc.contributor.author Helliwell, K.E.
dc.contributor.author Harrison, E.L.
dc.contributor.author Christie-Oleza, J.A.
dc.contributor.author Rees, A.P.
dc.contributor.author Kleiner, F.H.
dc.contributor.author Gaikwad, T.
dc.contributor.author Downe, J.
dc.contributor.author Aguilo-Ferretjans, M.M.
dc.contributor.author Al-Moosawi, L.
dc.contributor.author Brownlee, C.
dc.contributor.author Wheeler, G.L.
dc.date.accessioned 2021-11-12T09:39:27Z
dc.date.available 2021-11-12T09:39:27Z
dc.identifier.uri http://hdl.handle.net/11201/156115
dc.description.abstract [eng] Diatoms are a diverse and globally important phytoplankton group, responsible for an estimated 20% of carbon fixation on Earth. They frequently form spatially extensive phytoplankton blooms, responding rapidly to increased availability of nutrients, including phosphorus (P) and nitrogen (N). Although it is well established that diatoms are common first responders to nutrient influxes in aquatic ecosystems, little is known of the sensory mechanisms that they employ for nutrient perception. Here, we show that P-limited diatoms use a Ca2+-dependent signaling pathway, not previously described in eukaryotes, to sense and respond to the critical macronutrient P. We demonstrate that P-Ca2+ signaling is conserved between a representative pennate (Phaeodactylum tricornutum) and centric (Thalassiosira pseudonana) diatom. Moreover, this pathway is ecologically relevant, being sensitive to sub-micromolar concentrations of inorganic phosphate and a range of environmentally abundant P forms. Notably, we show that diatom recovery from P limitation requires rapid and substantial increases in N assimilation and demonstrate that this process is dependent on P-Ca2+ signaling. P-Ca2+ signaling thus governs the capacity of diatoms to rapidly sense and respond to P resupply, mediating fundamental cross-talk between the vital nutrients P and N and maximizing diatom resource competition in regions of pulsed nutrient supply.
dc.format application/pdf
dc.relation.isformatof Versió postprint del document publicat a: https://doi.org/10.1016/j.cub.2020.11.073
dc.relation.ispartof Current Biology, 2021, vol. 31, num. 5, p. 978-989
dc.subject.classification 57 - Biologia
dc.subject.other 57 - Biological sciences in general
dc.title A novel Ca2+ signaling pathway coordinates environmental phosphorus sensing and nitrogen metabolism in marine diatoms.
dc.type info:eu-repo/semantics/article
dc.type info:eu-repo/semantics/acceptedVersion
dc.date.updated 2021-11-12T09:39:27Z
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.identifier.doi https://doi.org/10.1016/j.cub.2020.11.073

Files in this item

This item appears in the following Collection(s)

Show simple item record

Search Repository

Advanced Search


My Account