[eng] Introduction: Obesity is the most common metabolic disorder in developed society and has a multifactorial origin. In this paper, we assess that affects how the Mediterranean diet and regular physical exercise in the prevalence of obesity in the population studied. Materials and methods: A descriptive, cross-sectional study was carried out in 1457 workers in the Spanish Mediterranean area to determine the influence of adherence to the Mediterranean diet, assessed with the PREDIMED questionnaire, and physical activity, quantified with the IPAQ questionnaire, on the values of different scales of overweight and obesity. Results: Most of the overweight and obesity scales and body fat estimation scales analyzed show an improvement in values as the level of physical activity increases, both in men and women. A similar situation is observed with adherence to the Mediterranean diet. Conclusions: Physical activity and heart-healthy eating improve overweight and obesity-related scales