Cribado de neoplasia intraepitelial anal en pacientes con infección por virus de la inmunodeficiencia humana

Abstract

[eng] Introduction: The incidence of anal cancer has increased in recent years, making screening and early detection of anal intraepithelial neoplasia (AIN) a necessity in patients at risk. Methods: A descriptive observational study of homosexual patients (MSM) or women with CIN III, with human immunodeficiency virus (HIV) infection included in an AIN detection screening program was carried out between March 2016 and September 2019. Results: We have performed 695 anal smears, 156 with results of LSIL (low-grade lesion) or HSIL (high-grade lesion) (22.4%), 116 high resolution anoscopy (HRA) 75.3% of patients with altered cytology. We have 403 biopsies being 84% pathological, 197 biopsies of AIN 1 (49%), 96 AIN II and III (24%), 44 were condylomas (11%) and the rest, 16%, normal mucosa. Conclusion: The high prevalence of premalignant lesions and the improvement in the staging of lesions after treatment recommend this protocol.